Structure of PDB 7nbu Chain l Binding Site BS03

Receptor Information
>7nbu Chain l (length=135) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAAR
RAMTRAVKRQGKIWIRVFPDKPITEKPLAVRGKGKGNVEYWVALIQPGKV
LYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
Ligand information
Ligand IDMS6
InChIInChI=1S/C5H13NS2/c1-8-3-2-5(6)4-7/h5,7H,2-4,6H2,1H3/t5-/m0/s1
InChIKeyNSPBTQHSHXESOT-YFKPBYRVSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7CSCCC(CS)N
ACDLabs 12.01C(N)(CS)CCSC
CACTVS 3.385CSCC[C@H](N)CS
OpenEye OEToolkits 2.0.7CSCC[C@@H](CS)N
CACTVS 3.385CSCC[CH](N)CS
FormulaC5 H13 N S2
Name(2S)-2-amino-4-(methylsulfanyl)butane-1-thiol
ChEMBLCHEMBL36661
DrugBank
ZINC
PDB chain7nbu Chain l Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7nbu Substrate recognition and cryo-EM structure of the ribosome-bound TAC toxin of Mycobacterium tuberculosis.
Resolution3.11 Å
Binding residue
(original residue number in PDB)		X81 G83
Binding residue
(residue number reindexed from 1)		X81 G82
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006413 translational initiation
GO:1904689 negative regulation of cytoplasmic translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nbu, PDBe:7nbu, PDBj:7nbu
PDBsum7nbu
PubMed35552387
UniProtP0A7M9|RL31_ECOLI Large ribosomal subunit protein bL31 (Gene Name=rpmE);
P0ADY7|RL16_ECOLI Large ribosomal subunit protein uL16 (Gene Name=rplP)

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