Structure of PDB 3j81 Chain i Binding Site BS03

Receptor Information
>3j81 Chain i (length=111) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTKGGKKGRRGKNDSDGPKRELIYKEEGQEYAQITKMLGNGRVEASCFDG
NKRMAHIRGKLRKKVWMGQGDIILVSLRDFQDDQCDVVHKYNLDEARTLK
NQGELPENAKI
Ligand information
>3j81 Chain 3 (length=22) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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......................
Receptor-Ligand Complex Structure
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PDB3j81 Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		K7 K10 R13 K67 W70
Binding residue
(residue number reindexed from 1)		K3 K6 R9 K63 W66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0031369 translation initiation factor binding
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0001677 formation of translation initiation ternary complex
GO:0001731 formation of translation preinitiation complex
GO:0001732 formation of cytoplasmic translation initiation complex
GO:0002188 translation reinitiation
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm
GO:0010494 cytoplasmic stress granule
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3j81, PDBe:3j81, PDBj:3j81
PDBsum3j81
PubMed25417110
UniProtP38912|IF1A_YEAST Eukaryotic translation initiation factor 1A (Gene Name=TIF11)

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