Structure of PDB 5t5h Chain f Binding Site BS03

Receptor Information
>5t5h Chain f (length=397) Species: 5693 (Trypanosoma cruzi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EHPRHGHLGFLPRKRSRQIRGRVRSFPKDDPSQKPHLTSFMVFKAGMTHI
VRDVDRPGSKVNKKEVVEPVTILEAPPMVVVGIVGYRQTPVGHKTIGTVW
AHHTSVEFRRRFYKNWKQSAQLAFTKRKQFARTTEGRLAEARTLKAFAKK
ADIIRVVAHTQLRKLRNNRVGVKKAHVSEIQINGGTIAEKIELAKSLLEK
EVRIDSIFQQSETCDVCAVTKGHGFTGVVKRWGVACLPRKTHRGLRKVAC
IGAWHPARVMYTVARAGQHGYHHRTHLNKKIYQLGRAVSMEPNQATTTYD
LTAKSITPMGGFVGYGTVRNDYIMLKGSVAGPRRRVITLRRPMAPQTSRK
LTEQITLKFIDTSSKIGHGRFQTKKEKSQWFGPLKKDRIRREERLRK
Ligand information
>5t5h Chain G (length=121) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguaucgugaggguaguacgagguacucccaugccgugccucugguuucu
ggaguuugucgaacggcaagugcuccgacgcuaucgcacggugguuagcc
agucccaagaccagaugccca
<<<<<<....<<<..<<<.<.<<...>>.>.>>><<<<<...<<<<....
<<<<<<<<<......>>>>..>>>>>...>>>>..>>>>>.<<<<..>>>
>..>>>.......>>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5t5h Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		G12 H13 L14 G15 F16 L17 R19 K20 R23 R26 R30 S31 K50 M53 T54 H55 R62 P63 G64 S65 P75 Y92 H99 K100 T101 G103 T104 W106 F118 K120 L128 A129 F130 T131 K132 R133 R161 S184 E185 T226 K227 H229 Y267 H279 R280 T281 H282 L283 N284 K285 K332 G333 S334 V335 A336 G337 R339 R346 M349 R355 K371 I372 G373 H374
Binding residue
(residue number reindexed from 1)		G6 H7 L8 G9 F10 L11 R13 K14 R17 R20 R24 S25 K44 M47 T48 H49 R56 P57 G58 S59 P69 Y86 H93 K94 T95 G97 T98 W100 F112 K114 L122 A123 F124 T125 K126 R127 R155 S178 E179 T220 K221 H223 Y261 H273 R274 T275 H276 L277 N278 K279 K326 G327 S328 V329 A330 G331 R333 R340 M343 R349 K365 I366 G367 H368
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5t5h, PDBe:5t5h, PDBj:5t5h
PDBsum5t5h
PubMed27791004
UniProtV5B599

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