Structure of PDB 6ks6 Chain d Binding Site BS03

Receptor Information
>6ks6 Chain d (length=524) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VPSNATFKNKEKPQEVRKANIIAARSVADAIRTSLGPKGMDKMIKTSRGE
IIISNDGHTILKQMAILHPVARMLVEVSAAQDSEAGDGTTSVVILTGALL
GAAERLLNKGIHPTIIADSFQSAAKRSVDILLEMCHKVSLSDREQLVRAA
STSLSSKIVSQYSSFLAPLAVDSVLKISDENSKNVDLNDIRLVKKVGGTI
DDTEMIDGVVLTQTAIKSAGGPTRKEKAKIGLIQFQISPPKPDTENNIIV
NDYRQMDKILKEERAYLLNICKKIKKAKCNVLLIQKSILRDAVNDLALHF
LSKLNIMVVKDIEREEIEFLSKGLGCKPIADIELFTEDRLGSADLVEEID
SDGSKIVRVTGIRNNNARPTVSVVIRGANNMIIDETERSLHDALCVIRCL
VKERGLIAGGGAPEIEISRRLSKEARSMEGVQAFIWQEFASALEVIPTTL
AENAGLNSIKVVTELRSKHENGELNDGISVRRSGTTNTYEEHILQPVLVS
TSAITLASECVKSILRIDDIAFSR
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain6ks6 Chain d Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6ks6 An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity.
Resolution2.99 Å
Binding residue
(original residue number in PDB)		D60 T93 T94 K161 D396
Binding residue
(residue number reindexed from 1)		D56 T89 T90 K157 D392
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D60 T93 T94 D396
Catalytic site (residue number reindexed from 1) D56 T89 T90 D392
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0051086 chaperone mediated protein folding independent of cofactor
Cellular Component
GO:0005737 cytoplasm
GO:0005832 chaperonin-containing T-complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ks6, PDBe:6ks6, PDBj:6ks6
PDBsum6ks6
PubMed31492816
UniProtP39078|TCPD_YEAST T-complex protein 1 subunit delta (Gene Name=CCT4)

[Back to BioLiP]