Structure of PDB 8ip8 Chain bl Binding Site BS03

Receptor Information
>8ip8 Chain bl (length=437) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSDSHETDKNIEMWKIKKLIKGLESARGNGTSMISLIMPPRDQVSRVTKM
LGDEYGTASNIKSRVNRQSVLGAITSAQQRLKLYNRVPPNGLVLYTGTIV
TDDGKEKKVTIDFEPFKPINASLYLCDNKFHTEALSELLESDDKFGFIIM
DGNGTLFGTLSGNTREVLHKFSVDLPKKHGRGGQSALRFARLRMEKRHNY
VRKTAELATQFFINPATSQPNVAGLILAGSADFKTELSQSDMFDQRLQCK
ILNVVDVSYGGESGFNQAIELSAEILANVKFIQEKKLIGKYFEEISQDTG
KYVFGVDDTLKALEMGAVETLMVWENLDVNRFVLKHSATGEIIIKHLNKE
GEADQSNFRDPSTNAELEVQEKTSLLEWFANEYKKFGCTLEFVTNKSQEG
SQFCRGFGGIGGILRYQLDIRSFDDLDDDEGVYEDSD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ip8 Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		T31 T57 N60 I61 K62
Binding residue
(residue number reindexed from 1)		T31 T57 N60 I61 K62
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
GO:1990825 sequence-specific mRNA binding
Biological Process
GO:0002184 cytoplasmic translational termination
GO:0006412 translation
GO:0006415 translational termination
GO:0060255 regulation of macromolecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0018444 translation release factor complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ip8, PDBe:8ip8, PDBj:8ip8
PDBsum8ip8
PubMed38267667
UniProtI3NM28

[Back to BioLiP]