Structure of PDB 6hrm Chain a Binding Site BS03

Receptor Information

>6hrm Chain a (length=66) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRD
VATGGRVDRFNKRFNI

Ligand information

InChI=1S/Zn/q+2

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Zn

Name

ZINC ION

PDB chain

6hrm Chain a Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	6hrm Controlling orthogonal ribosome subunit interactions enables evolution of new function.
Resolution	2.96 Å
Binding residue (original residue number in PDB)	S17 D35
Binding residue (residue number reindexed from 1)	S17 D35
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0008270	zinc ion binding
GO:0019843	rRNA binding
GO:0046872	metal ion binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0006413	translational initiation
GO:1904689	negative regulation of cytoplasmic translational initiation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Cellular Component

External links

PDB	RCSB:6hrm, PDBe:6hrm, PDBj:6hrm
PDBsum	6hrm
PubMed	30518861
UniProt	P0A7M9\|RL31_ECOLI Large ribosomal subunit protein bL31 (Gene Name=rpmE)

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