Structure of PDB 5lmv Chain a Binding Site BS03

Receptor Information
>5lmv Chain a (length=502) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQEKLAEEERRKSLPRRPPVVVIMGHVDHGKTTLLDYLRKSRIAEKEAGG
ITQHVGAFEVKTPQGTVVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADD
GIMPQTEEAIAHAKAAGAKLIFAINKIDLPQADPEKVKRQLMERGFVPEE
YGGDAIVIPISAKTGQGVQDLLEMILLLAELEDYRAPNAEPRGVILESKL
DKQAGIIANMLVQEGTFRVGDYVVAGEAYGRIRAMMDADGNQRKEAGPGS
AVQVLGFQELPHAGDVVEWVPDLEAAKEIAEERKEERKAREEEEKARRPR
TMAELLRAMQEEGRKELNLILRADTQGSLEAIQHILARESTEDVKINILL
AQVGAPTESDVLLAQTANAAILAFGVNPPGSVKKKAEEKGVLLKTFRIIY
DLVDEVRNMVKGQRLGQAEVRAIFRLPTGKQVAGCMVTQGRIPRNAEVRV
LRDGQVIWQGRIASLKRFKEDVREVAQGYECGIGLDGFDDFREGDVIEAF
QM
Ligand information
Ligand IDFME
InChIInChI=1S/C6H11NO3S/c1-11-3-2-5(6(9)10)7-4-8/h4-5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
InChIKeyPYUSHNKNPOHWEZ-YFKPBYRVSA-N
SMILES
SoftwareSMILES
CACTVS 3.341CSCC[C@H](NC=O)C(O)=O
CACTVS 3.341CSCC[CH](NC=O)C(O)=O
ACDLabs 10.04O=CNC(C(=O)O)CCSC
OpenEye OEToolkits 1.5.0CSCCC(C(=O)O)NC=O
OpenEye OEToolkits 1.5.0CSCC[C@@H](C(=O)O)NC=O
FormulaC6 H11 N O3 S
NameN-FORMYLMETHIONINE
ChEMBL
DrugBankDB04464
ZINCZINC000001529464
PDB chain5lmv Chain Z Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5lmv Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Resolution4.9 Å
Binding residue
(original residue number in PDB)		R485 G498 F532 E544
Binding residue
(residue number reindexed from 1)		R421 G434 F468 E480
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) K86 T87 T107 H130
Catalytic site (residue number reindexed from 1) K31 T32 T52 H75
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003743 translation initiation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5lmv, PDBe:5lmv, PDBj:5lmv
PDBsum5lmv
PubMed27662086
UniProtP48515|IF2_THET8 Translation initiation factor IF-2 (Gene Name=infB)

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