Structure of PDB 1p8k Chain Z Binding Site BS03

Receptor Information
>1p8k Chain Z (length=254) Species: 162425 (Aspergillus nidulans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSDLTYAYLVGLFEGDGYFSITKKGKYLTYELGIELSIKDVQLIYKIKKI
LGIGIVSFRKRNEIEMVALRIRDKNHLKSFILPIFEKYPMFSNKQYDYLR
FRNALLSGIISLEDLPDYTRSDEPLNSIESIINTSYFSAWLVGFIEAEGC
FSVYKLNKDDDYLIASFDIAQRDGDILISAIRKYLSFTTKVYLDKTNCSK
LKVTSVRSVENIIKFLQNAPVKLLGNKKLQYLLWLKQLRKISRYSEKIKI
PSNY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1p8k Structural and biochemical analyses of DNA and RNA binding by a bifunctional homing endonuclease and group I intron splicing factor.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		D16 E35 L36 S37 M66 Y162 K190 Y192 K200 T204 S205 V206 R243
Binding residue
(residue number reindexed from 1)		D16 E35 L36 S37 M66 Y162 K190 Y192 K200 T204 S205 V206 R243
Binding affinityPDBbind-CN: Kd=11nM
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:1p8k, PDBe:1p8k, PDBj:1p8k
PDBsum1p8k
PubMed14633971
UniProtP03880|ANI1_EMEND Intron-encoded DNA endonuclease I-AniI (Gene Name=I-AniI)

[Back to BioLiP]