Structure of PDB 3np2 Chain X Binding Site BS03

Receptor Information

>3np2 Chain X (length=172) Species: 9796 (Equus caballus)

SQIRQNYSTEVEAAVNRLVNLYLRASYTYLSLGFYFDRDDVALCGVAHFF
RELAEEKREGAERLLKMQNQRGGRALFQDLQKPSQDEWGTTLDAMKAAIV
LEKSLNQALLDLHALGSAQADPHLCDFLESHFLDEEVKLIKKMGDHLTNI
QRLVGSQAGLGEYLFERLTLKH

Ligand information

• Ligand ID: PD
• InChI: InChI=1S/Pd/q+2
• InChIKey: MUJIDPITZJWBSW-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Pd++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Pd+2]
• Formula: Pd
• Name: PALLADIUM ION
• PDB chain: 3np2 Chain X Residue 178

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3np2 Definite coordination arrangement of organometallic palladium complexes accumulated on the designed interior surface of apo-ferritin.
• Resolution: 1.86 Å
• Binding residue (original residue number in PDB): C45 H49
• Binding residue (residue number reindexed from 1): C44 H48
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0008198 ferrous iron binding
• GO:0008199 ferric iron binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006826 iron ion transport
• GO:0006879 intracellular iron ion homeostasis
• GO:0006880 intracellular sequestering of iron ion

Cellular Component

• GO:0005737 cytoplasm
• GO:0005764 lysosome
• GO:0005776 autophagosome
• GO:0031410 cytoplasmic vesicle
• GO:0044754 autolysosome
• GO:0070288 ferritin complex

External links

• PDB: RCSB:3np2, PDBe:3np2, PDBj:3np2
• PDBsum: 3np2
• PubMed: 20730233
• UniProt: P02791|FRIL_HORSE Ferritin light chain (Gene Name=FTL)