Structure of PDB 2zvq Chain X Binding Site BS03

Receptor Information
>2zvq Chain X (length=288) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVFRRELVDVEGIPLFWSIAEHWSQVESFEARPDDILISTYPKSGTTWVS
EILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGITNGVEMLNNMPSPRIV
KTHLPVQLLPSSFWKNDCKIIYVARNAKDVVVSYYYFYQMAKIHPEPGTW
EEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYRILYLFYEDMKENPKCEIQ
KILKFLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEEMDHSVSPF
MRKGISGDWKNQFTVAQYEKFEEDYVKKMEDSTLKFRS
Ligand information
Ligand ID1NP
InChIInChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H
InChIKeyKJCVRFUGPWSIIH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1ccc2c(c1)cccc2O
ACDLabs 10.04Oc2cccc1ccccc12
CACTVS 3.341Oc1cccc2ccccc12
FormulaC10 H8 O
Name1-NAPHTHOL;
naphthalen-1-ol
ChEMBLCHEMBL122617
DrugBank
ZINCZINC000004292977
PDB chain2zvq Chain X Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB2zvq Structural basis for the broad range substrate specificity of a novel mouse cytosolic sulfotransferase--mSULT1D1
Resolution1.3 Å
Binding residue
(original residue number in PDB)		A129 R130 N131 W172 F192 E194 K290 F291 R292
Binding residue
(residue number reindexed from 1)		A124 R125 N126 W167 F187 E189 K285 F286 R287
Annotation score1
Enzymatic activity
Enzyme Commision number 2.8.2.-
Gene Ontology
Molecular Function
GO:0004062 aryl sulfotransferase activity
GO:0008146 sulfotransferase activity
GO:0016740 transferase activity
Biological Process
GO:0000103 sulfate assimilation
GO:0006584 catecholamine metabolic process
GO:0006629 lipid metabolic process
GO:0051923 sulfation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2zvq, PDBe:2zvq, PDBj:2zvq
PDBsum2zvq
PubMed19073143
UniProtQ3UZZ6|ST1D1_MOUSE Sulfotransferase 1 family member D1 (Gene Name=Sult1d1)

[Back to BioLiP]