Structure of PDB 7ajt Chain UG Binding Site BS03

Receptor Information
>7ajt Chain UG (length=533) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KERENQNKFERSTYQTKDKKLRAGLKKIDEQYKKAVSSAAATDYLLPESN
GYLEPENELEKTFKVQQSEIKSSVDVSTANKALDLSLKEFGPYHIKYAKN
GTHLLITGRKGHVASMDWRKGQLRAELFLNETCHSATYLQNEQYFAVAQK
KYTFIYDHEGTELHRLKQHIEARHLDFLPYHYLLVTAGETGWLKYHDVST
GQLVSELRTKAGPTMAMAQNPWNAVMHLGHSNGTVSLWSPSMPEPLVKLL
SARGPVNSIAIDRSGYYMATTGADRSMKIWDIRNFKQLHSVESLPTPGTN
VSISDTGLLALSRGPHVTLWKDALKLSGDSKPCFGSMGGNPHRNTPYMSH
LFAGNKVENLGFVPFEDLLGVGHQTGITNLIVPGAGEANYDALELNPFET
KKQRQEQEVRTLLNKLPADTITLDPNSIGSVDKRSSTIRLNAKDLAQTTM
DANNKAKTNSDIPDVKPDVKGKNSGLRSFLRKKTQNVIDERKLRVQKQLD
KEKNIRKRNHQIKQGLISEDHKDVIEEALSRFG
Ligand information
>7ajt Chain D4 (length=230) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucauaggaucauuucuauaggaaucgucacucuuugacu
cuucaaaagagccacugaauccaacuugguugaugagucccauaaccuuu
guacccgugagaaauagcuugguccgcaauccuuagcgguucggccaucu
auaauuuugaauaaaaauuuugccguugcuauggcgcgaugaucuaccca
uggguggguacaaauggcagucugacaagu
..................................................
.......................<<<<<.................<<<<<
<<<<<.<.......<<...<<<.<<<.<<<<......>>>>>>>>>>..>
>.<<<<<......>>.>>>..<<<<......>>>>........>.<<<..
..>>>.>>>>>>>>.>>........>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ajt Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Resolution4.6 Å
Binding residue
(original residue number in PDB)		T221 L414 E427 R431
Binding residue
(residue number reindexed from 1)		T200 L393 E406 R410
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0030688 preribosome, small subunit precursor
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ajt, PDBe:7ajt, PDBj:7ajt
PDBsum7ajt
PubMed33326748
UniProtP40055|UTP7_YEAST U3 small nucleolar RNA-associated protein 7 (Gene Name=UTP7)

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