Structure of PDB 8rxx Chain ST Binding Site BS03 |
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| >8rxx Chain S1 (length=1836)
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gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcagcaggaaucugcgcauggcucauuaaa
ucagacguaaucugccgcaaaaaucuugcggccgcaaaauuggauaacuu
ggcgaaacgccaagcuaauacaugaaccaaccggguguucuccacgugag
acgcccagcgaaugaaugacaguaaaaccaaugccuugcaguaacaccca
gcaguguugacucaauucauuccgugcgaaagccggcuuguuccggcguc
uuuugacgaacaacugcccuaucagcuggugauggccguguaguggacug
ccauggcguugacgggagcgggggauuaggguucgauuccggagagggag
ccugagaaauagcuaccacuucuacggagggcagcaggcgcgcaaauugc
ccaaugucaaaacaaaacgaugaggcagcgaaaagaaauagaguuguuug
ucauuucaaugggggauauuuaaacccauccaauaucgaguaacaauugg
aggacaagucuggugccagcacccgcgguaauuccagcuccaaaagcgua
uauuaaugcuguugcuguuaaaggguucguaguugaacugugggcugugc
agggcccuugcagcccgugaaaagaaacaagaaacacgggagugggucgc
augucaugcaugccagggggcguccgugauuuuuacugugacuaaagaag
cgugacuaaagcagucauuugacuugaauuagaaagcaugggauaacaaa
ggagcagccucuaggcuaccguuucggcuuuuguuguuuuuaaaggucua
uuggagauuauggagcuguuucccacggugugacggccucuaggaaugaa
ggaggguaguucgggggagaacguacuggggcgucagaggugaaauucuu
agaccgcaccaagacgaacuacagcgaaggcauucuucaaggauaccuuc
cucaaucaagaaccaaaguguggagaucgaagaugauuagaaaccauugu
aguccacacugcaaacgaugacacccaugaauuggggauacuuaguaucu
uuacgggaauauccucagcacgcacgcgaaagcuuugagguuacagucuc
aggggggaguacguucgcaagagugaaacuuaaagaaauugacggaaugg
caccacaagacguggagcgugcgguuuaauuugacucaacacggggaacu
uuaccagauccggacaggaugagauugacagauugaguguucuuucucga
uucccugaaugguggugcauggccgcuuauggucgguggagugauuuguu
ugguugauuccgucaacggacgagauccaagcugcccaguagaauucaga
auugcccauaggauagcgcauucggucgaauucuucucugcgggauuccu
uuguaauugcacaaggugaaauuuugggcaacagcaggucugugaugcuc
cucaauguucugggcgacacgcgcacuacaaugucagugagaacaagaaa
acgaaccuacuugaucaaaagaguggggaaaccccggaaucacauagacc
cacuugggaccgaggauugcaauuuggucgcgcaacgaggaaugucucgu
aggcgcagcucaucaaacugugccgauuacgucccugccauuuguacaca
ccgcccgucguuguuuccgaugauggugcaauacaggugaucggacaggc
gcccgaaaguucaccgauauuucuucaauagaggaagcaaaagucguaac
aagguagcuguaggggaaccugcagcugggacauuu |
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<<<..........<<<
.<<<..<<....<<....<<<<.>>>>...>>.>>......<<.......
.<<<..<<..<<...<<.<<.....<<<<<..>>>>>...<<.....<<<
<<<.....>>>>>>......>>..........<<<<<.<<<<.....>>>
>>>>>>.<<<<<<<<<<.....(((((.((((<<...>>...........
..............>>>>>>>>...>>....<<<<<......>>>>>...
>>.>>..>>>>..>>>.<<<....<<<....<<<<<.<<.......>>.>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<.<<
<..........>>>.>>.<<<<....>>>>...>>>>>>.........<<
<....<<<..........>>>..>>>.......>>>....<<<.<<....
.>>.>>>.....<<<<............>>>.....>.........<<<<
<((......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>
>>>>>.........<<<[[.....<<<<...<<<.......<...<<...
.<..>...>>...>..................<...............<<
<<.......>>>>.............>.....<<<<<<<<.......<<.
..<.......>..<<<....>>>.....>>......>>>>>..>>>....
.......<<..<<<<<<.<<.....>>.<...)))).)))))>.>>>>>>
..>>.......<<<<<<<.<.<<...>>.>...>>>.>>>>.........
...<<<<<..<<...<<<<<<<<<.<<<<.<<<...<<<......>>>..
....>>>.>>>.>>>>.......<<....>>.>>>>>>..>>.>>>.>>.
...>>>...>>>>...<<<<<<<<...<...<<<<.<.....>.>>>>..
.>>>>>>>>>.........<<<.<<..<<..<<<<<<<........<<..
........>>.>>>>>>>..>>...<<..]]>>.....>>.....>>>.>
>>.<<<......<<<<....>>>>....>>>..]]]].}<<<<<.<<<<<
<<..<<.<<<<<<..<<.<<<<<<<......<<........>>.......
...<<<<<.<....<<<<........<<.<<<........>>>.>>....
...>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>...
<<<......>>>...>>.>>>....<<<<<.<<<<.....<<<<<<<.<<
<<.................>>>>....>>>>>>>.....>>>>....<<<
<.<<......>>>>>>.......>>>>>....>>>.>>>.....>>>>>>
>.....>.>>>>>...>>.>>>>>.>>.....<<<.<<<<......<...
.....<<<<<<<........>>>>>>>....>.......>>>>...>>>.
..........<<<..<........>..>>>...........>>>>>>...
.<<<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<.<<<<<<<<..<<.<<<.<.<<<<..<<<<<.....<.<<.
.>>.>.....>>>>>..>>>>.>.>>>.>>..>>>>>>>>..>.>>...>
.....<<<<<<<<<....>>>>>>>>>......... |
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| PDB | 8rxx Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. |
| Resolution | 2.97 Å |
Binding residue
(original residue number in PDB) | V2 R3 M4 H5 N7 G8 R9 G10 K11 A12 S13 S14 A15 L16 P17 R20 S48 M52 R55 A61 Q62 K64 G68 R69 K70 I71 L72 R73 H77 D87 F90 R94 M98 H101 H105 T107 D108 D110 Y113 R114 L117 S120 R121 R124 R127 Y128 V132 K133 Q134 |
Binding residue
(residue number reindexed from 1) | V1 R2 M3 H4 N6 G7 R8 G9 K10 A11 S12 S13 A14 L15 P16 R19 S47 M51 R54 A60 Q61 K63 G67 R68 K69 I70 L71 R72 H76 D86 F89 R93 M97 H100 H104 T106 D107 D109 Y112 R113 L116 S119 R120 R123 R126 Y127 V131 K132 Q133 |
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