Structure of PDB 7tf6 Chain S Binding Site BS03

Receptor Information
>7tf6 Chain S (length=438) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFTKEDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQLEKVLDNEMMF
DGSSIEGFVRIEESDMYLHPDLDTWVIFPWGKVARLICDVYKTDGTPFEG
DPRANLKRVLKEMEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGY
FDLAPTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVT
ACDNIQTFKLVVKTIARKHNLHATFMPKPLFGVNGSGMHFNVSLFKGKEN
AFFDPNTEMGLTETAYQFTAGVLKNARGFTAVCNPLVNSYKRLVPGYEAP
CYIAWSGKNRSPLIRVPSSRGLSTRIEVRSVDPAANPYMALAAILEAGLD
GIKNKLKVPEPVNQNIYEMNREEREAVGIQDLPSTLYTALKAMRENEVIK
KALGNHIYNQFINSKSIEWDYYRTQVSEWERDQYMKQY
Ligand information
>7tf6 Chain W (length=11) Species: 1280 (Staphylococcus aureus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PINRGDLSRFI
Receptor-Ligand Complex Structure
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PDB7tf6 Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		Q441 Q445
Binding residue
(residue number reindexed from 1)		Q433 Q437
Enzymatic activity
Enzyme Commision number 6.3.1.2: glutamine synthetase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004356 glutamine synthetase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006542 glutamine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tf6, PDBe:7tf6, PDBj:7tf6
PDBsum7tf6
PubMed35778410
UniProtE3VXC2

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