Structure of PDB 7aqc Chain R Binding Site BS03

Receptor Information
>7aqc Chain R (length=558) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFDGMFTYGMTHELNEKIMGGRITKIHQPYKHDVIFHIRAKGKNQKLLLS
AHPSYSRVHITAQAYENPSEPPMFCMLLRKHIEGGFIEKIEQAGLDRIMI
FHIKSRNEIGDETVRKLYVEIMGRHSNIILTDAAENVIIDGLKHLSPSMN
SYRTVLPGQDYKLPPAQDKISPLEASEDDILRHLSFQEGRLDKQIVDHFS
GVSPLFAKEAVHRAGLANKVTLPKALLALFAEVKEHRFIPNITTVNGKEY
FYLLELTHLKGEARRFDSLSELLDRFYFGKAERDRVKQQAQDLERFVVNE
RKKNANKIKKLEKTLEYSENAKEFQLYGELLTANLYMLKKGDKQAEVINY
YDEESPTITIPLNPNKTPSENAQAYFTKYQKAKNSVAVVEEQIRLAQEEI
EYFDQLIQQLSSASPRDISEIREELVEGKYLRPHNPVLETYESTSGLTIL
VGKNNRQNEYLTTRVAARDDIWLHTKDIPGSHVVIRSSEPDEQTIMEAAT
IAAYFSKAKDSSSVPVDYTKIRHVKKPNGAKPGFVTYDSQHTVFVTPDAD
TVIKLKKS
Ligand information
>7aqc Chain T (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggccuuagcucagcugggagagcgccugcuuugcacgcaggaggucag
cgguucgaucccgcuaggcuccacca
<<<<<<<..<<<<........>>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
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PDB7aqc Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC.
Resolution2.99 Å
Binding residue
(original residue number in PDB)		D97 R98 M123 R125 H126 K144 N151 R154 P165 P166 Q168 G202 V203 S204 K304 K308 K311 K382 S386 V389 Q393 R433
Binding residue
(residue number reindexed from 1)		D96 R97 M122 R124 H125 K143 N150 R153 P164 P165 Q167 G201 V202 S203 K303 K307 K310 K381 S385 V388 Q392 R432
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0043023 ribosomal large subunit binding
Biological Process
GO:0006412 translation
GO:0072344 rescue of stalled ribosome
Cellular Component
GO:1990112 RQC complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aqc, PDBe:7aqc, PDBj:7aqc
PDBsum7aqc
PubMed33259811
UniProtO34693|RQCH_BACSU Rqc2 homolog RqcH (Gene Name=rqcH)

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