Structure of PDB 6cnc Chain R Binding Site BS03

Receptor Information
>6cnc Chain R (length=522) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVALESREATL
NNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCL
YVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVKKLHITELPLADPSL
FIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILL
ACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDV
EDGEARPPSFVKNRKKESGIVPTLQNIVATVTLGCRLDLKTVALHARNAE
YNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARII
QKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGL
IYRMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRKMSGS
PRNLHLLPTTDTYLSKVSDDPDNLEDVDDEELNAHLLNEEASKLKERIWI
GLNADFLLEQESKRLKQEADIA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6cnc Chain R Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6cnc Structural visualization of RNA polymerase III transcription machineries.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		C4 C28
Binding residue
(residue number reindexed from 1)		C4 C28
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0017025 TBP-class protein binding
Biological Process
GO:0006352 DNA-templated transcription initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:6cnc, PDBe:6cnc, PDBj:6cnc
PDBsum6cnc
PubMed30083386
UniProtP13393|TBP_YEAST TATA-box-binding protein (Gene Name=SPT15);
P29056|TF3B_YEAST Transcription factor IIIB 70 kDa subunit (Gene Name=BRF1)

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