Structure of PDB 5j3c Chain QY Binding Site BS03

Receptor Information

>5j3c Chain QY (length=259) Species: 331111 (Escherichia coli O139:H28 str. E24377A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRV
EIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRI
HTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRI
THLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRN
LLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQ
EHQADQLAA

Ligand information

>5j3c Chain QV (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cgcgggguggagcagccugguagcucgucgggcucauaacccgaaggucg
ucgguucaaauccggcccccgcaacca

.<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<
<<<<.......>>>>>>>>>>>.....

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5j3c Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Resolution	3.04 Å
Binding residue (original residue number in PDB)	G233 G234 Q235 H236 E260 R261
Binding residue (residue number reindexed from 1)	G137 G138 Q139 H140 E164 R165

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003747	translation release factor activity
GO:0005515	protein binding
GO:0016149	translation release factor activity, codon specific
GO:0043022	ribosome binding

	Biological Process
GO:0006412	translation
GO:0006415	translational termination

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

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External links

PDB	RCSB:5j3c, PDBe:5j3c, PDBj:5j3c
PDBsum	5j3c
PubMed	27681416
UniProt	P0A7I0\|RF1_ECOLI Peptide chain release factor RF1 (Gene Name=prfA)

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