Structure of PDB 4yzv Chain QY Binding Site BS03

Receptor Information
>4yzv Chain QY (length=91) Species: 585 (Proteus vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIKSFKHKGLKLLFEKGVTSGVPAQDVDRINDRLQAIDTATEIGELNRQI
YKLHPLKGDREGYWSITVRANWRITFQFINGDAYILNYEDY
Ligand information
>4yzv Chain QX (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaggagguaaaaaugacau
....................
Receptor-Ligand Complex Structure
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PDB4yzv Defining the mRNA recognition signature of a bacterial toxin protein.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
H54 L56 K57 G58 N71 R73
Binding residue
(residue number reindexed from 1)
H54 L56 K57 G58 N71 R73
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0005515 protein binding
GO:0030371 translation repressor activity
GO:0043022 ribosome binding
Biological Process
GO:0006276 plasmid maintenance
GO:0006401 RNA catabolic process
GO:0008285 negative regulation of cell population proliferation
GO:0017148 negative regulation of translation
GO:0030308 negative regulation of cell growth

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Molecular Function

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Biological Process
External links
PDB RCSB:4yzv, PDBe:4yzv, PDBj:4yzv
PDBsum4yzv
PubMed26508639
UniProtQ7A225|HIGB_PROVU Endoribonuclease HigB (Gene Name=higB)

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