Structure of PDB 5mam Chain P Binding Site BS03

Receptor Information
>5mam Chain P (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
Ligand information
>5mam Chain O (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB5mam Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		C7 L11 L15 C19 R22 G23 F24 F25 Y26 T30
Binding residue
(residue number reindexed from 1)		C7 L11 L15 C19 R22 G23 F24 F25 Y26 T30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:5mam, PDBe:5mam, PDBj:5mam
PDBsum5mam
PubMed28348075
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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