Structure of PDB 5jus Chain O Binding Site BS03

Receptor Information
>5jus Chain O (length=169) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK
Ligand information
>5jus Chain EC (length=198) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuccauguauugguuacccaucugcaucgaaaacucuccgaacacua
ggugcaguaaggcuuucauggagugguuugcuauuuagcguacguguacc
auaggcagccccaaaaacacguaggagaaagucccagucacuuugggcaa
aguagacagccgcgcuugcguggugggacuuaauuaaugccugcuaac
...<<<<<<<..............<<<<<<..........[[........
.>>>>>>.........>>>>>>>.(((.<<<<<..>>>>>..<<<<<)))
...<<.....>>....>>>>>..]].......(((.(((..(..<<<<..
)...))).<..............>)))...........>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5jus Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		R55 T56
Binding residue
(residue number reindexed from 1)		R50 T51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5jus, PDBe:5jus, PDBj:5jus
PDBsum5jus
PubMed27159452
UniProtP0C0W9|RL11A_YEAST Large ribosomal subunit protein uL5A (Gene Name=RPL11A)

[Back to BioLiP]