Structure of PDB 7xhn Chain N Binding Site BS03

Receptor Information
>7xhn Chain N (length=305) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQ
HLIHLCEEKRASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFD
MKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPT
YVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDS
LKAIVFKQYNQDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQYKLE
TKFKEPLRCLIKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYF
KIRDK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xhn Structural insights into human CCAN complex assembled onto DNA.
Resolution3.71 Å
Binding residue
(original residue number in PDB)		L322 I336 R337
Binding residue
(residue number reindexed from 1)		L288 I302 R303
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000939 inner kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7xhn, PDBe:7xhn, PDBj:7xhn
PDBsum7xhn
PubMed36085283
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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