Structure of PDB 3u5z Chain N Binding Site BS03

Receptor Information

>3u5z Chain N (length=320) Species: 10665 (Tequatrovirus T4)

SMITVNEKEHILEQKYRPSTIDECILPAFDKETFKSITSKGKIPHIILHS
PSPGTGKTTVAKALCHDVNADMMFVNGSDCKIDFVRGPLTNFASAASFDG
RQKVIVIDEFDRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQ
SRCRVITFGQPTDEDKIEMMKQMIRRLTEICKHEGIAIADMKVVAALVKK
NFPDFRKTIGELDSYSSKGVLDAGILSLVTNDRGAIDDVLESLKNKDVKQ
LRALAPKYAADYSWFVGKLAEEIYSRVTPQSIIRMYEIVGENNQYHGIAA
NTELHLAYLFIQLACEMQWK

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3u5z Chain N Residue 800

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3u5z How a DNA polymerase clamp loader opens a sliding clamp.
• Resolution: 3.5 Å
• Binding residue (original residue number in PDB): T57 E108
• Binding residue (residue number reindexed from 1): T58 E109
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.6.4.-

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003689 DNA clamp loader activity
• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006260 DNA replication
• GO:0006261 DNA-templated DNA replication
• GO:0006281 DNA repair
• GO:0039686 bidirectional double-stranded viral DNA replication
• GO:0039693 viral DNA genome replication

Cellular Component

• GO:0005663 DNA replication factor C complex

External links

• PDB: RCSB:3u5z, PDBe:3u5z, PDBj:3u5z
• PDBsum: 3u5z
• PubMed: 22194570
• UniProt: P04526|LOADL_BPT4 Sliding-clamp-loader large subunit (Gene Name=44)