Structure of PDB 8rec Chain M Binding Site BS03

Receptor Information
>8rec Chain M (length=347) Species: 571 (Klebsiella oxytoca) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TAGTPSGNGVDYQDDELPVYQGETTQSLQDYLMWQVELTPFTDTDRAIAT
SIVDAVDDTGYLTIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAA
KDLRDCLLIQLSQFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLK
EEVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDVLVRKVNDRWVVELNSD
SRWLIKSLESANDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVE
MHESTISRVTTQKYLHSPRGIFELKYFFSSHVNTEGGGEASSTAIRALVK
KLIAAENPAKPLSDSKLTSMLSEQGIMVARRTVAKYRESLSIPPSNQ
Ligand information
>8rec Chain T (length=51) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaatgtgcaacagcatgatcgcggcaagctgcgtgcaaaagtcgtgccag
c
Receptor-Ligand Complex Structure
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PDB8rec Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		P110 D292 S293 M376 H377 T380 H406 T409 R456
Binding residue
(residue number reindexed from 1)		P18 D200 S201 M251 H252 T255 H281 T284 R331
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0016987 sigma factor activity

View graph for
Molecular Function
External links
PDB RCSB:8rec, PDBe:8rec, PDBj:8rec
PDBsum8rec
PubMed38170755
UniProtP06223|RP54_KLEOX RNA polymerase sigma-54 factor (Gene Name=rpoN)

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