Structure of PDB 8a98 Chain M Binding Site BS03

Receptor Information

>8a98 Chain M (length=203) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GAFMYLNELWKKKSSDVMRFIQRIRSWEFRHQHTVVRLRRPTRPEKARML
GYKTKQGFCVFRVRVRRGGRKRPVHKGITYGKPKTSGVLGMKLNKNNQAV
AEQRLGKRFGNLRVLNSYWVNMDSTFKWYEVIAVDPMCKTIRRDPRINWI
VNSVHKHREQRGLTSAGRKHRGLRHKGHKASKLRPSYRAAWRRNNRIVFL
RKR

Ligand information

>8a98 Chain 7 (length=160) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

aacgugucgcgauggaugacuuggcuuccuauuucguugaagaacgcagu
aaagugcgauaagugguaucaauugcagauucuauuaccgaaucuuugaa
cgcaaacggcgcaugggagaagcugugucauccccgugcaugccauauuc
ucagugucga

.........................................<<<<<<.((
.....>>>.....<<<<<......)).........>>>>.>...>>>...
.<<.....>><<<<<<<.<..<<...>>...>>>>>>>>...........
..........

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8a98 CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT
Resolution	2.46 Å
Binding residue (original residue number in PDB)	R38 Q57 F110 N112 D136
Binding residue (residue number reindexed from 1)	R37 Q56 F109 N111 D135

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:8a98, PDBe:8a98, PDBj:8a98
PDBsum	8a98
PubMed	38722744
UniProt	Q4Q6S3

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