Structure of PDB 5ylz Chain M Binding Site BS03

Receptor Information

>5ylz Chain M (length=185) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DEINEPPPNICEQCLGDEANIRMTKIPQGSECKICTLPFTLYHFKTSKRS
NNIIKTLICVRCATQRNICQCCMLDSRWHIPIQLRDHLISLVNEENVMTE
EAKNDMMKRFLSLKNVKLGGAQITTKSFFLYNIDASIPEWKITDTVSQLL
SLIVNHKAKCGGLRFQSSELGERFVSIFIIPWSSG

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

5ylz Chain M Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5ylz Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
Resolution	3.6 Å
Binding residue (original residue number in PDB)	C34 C37 C61 C64
Binding residue (residue number reindexed from 1)	C32 C35 C59 C62
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0017070	U6 snRNA binding
GO:0036002	pre-mRNA binding

	Biological Process
GO:0000398	mRNA splicing, via spliceosome
GO:0006397	mRNA processing
GO:0008380	RNA splicing

	Cellular Component
GO:0000974	Prp19 complex
GO:0005634	nucleus
GO:0005681	spliceosomal complex
GO:0071006	U2-type catalytic step 1 spliceosome
GO:0071007	U2-type catalytic step 2 spliceosome

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Cellular Component

External links

PDB	RCSB:5ylz, PDBe:5ylz, PDBj:5ylz
PDBsum	5ylz
PubMed	29153833
UniProt	P38241\|SLT11_YEAST Pre-mRNA-splicing factor SLT11 (Gene Name=ECM2)

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