Structure of PDB 8rxh Chain LU Binding Site BS03

Receptor Information
>8rxh Chain LU (length=122) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VAVRAKVGSRSYVRQKQLAKGKKVFKIDCSIPAADGIFSEDVLGNFEQFF
QDNTKLNGRKGKLSDKVRLSMNDNVLTISTTMAYRKKYFKYLTKKFLKKK
DLRDWIRILATGKGTYQLKYFN
Ligand information
>8rxh Chain L5 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuacgucccucuccaaacgagagaacaugcaugggcuggcaugagcggca
ugcuucuccgguggggcuccgucccgaggcgcugaaccuugaggccugaa
aauucaugcucagggacacu
....<<<<<<<<<.......>>>>....<<<<<<<<.<<.....<<<...
..............<<.......>>....>>>....>>.....>>>....
....>>>>>...>>>>>...
Receptor-Ligand Complex Structure
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PDB8rxh Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Resolution2.93 Å
Binding residue
(original residue number in PDB)
K7 V8 G9 R11 S12 R60
Binding residue
(residue number reindexed from 1)
K6 V7 G8 R10 S11 R59
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8rxh, PDBe:8rxh, PDBj:8rxh
PDBsum8rxh
PubMed38722744
UniProtQ4Q0X2

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