Structure of PDB 5wlc Chain LU Binding Site BS03

Receptor Information
>5wlc Chain LU (length=457) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIKTIKRSADDYVPVKSTQESQMPRNLNPELHPFERAREYTKALNATKL
ERMFAKPFVGQLGYGHRDGVYAIAKNYGSLNKLATGSADGVIKYWNMSTR
EEFVSFKAHYGLVTGLCVTQPRFHDKKPDLKSQNFMLSCSDDKTVKLWSI
NVDDYSNKNNEEGLIRTFDGESAFQGIDSHRENSTFATGGAKIHLWDVNR
LKPVSDLSWGADNITSLKFNQNETDILASTGSDNSIVLYDLRTNSPTQKI
VQTMRTNAICWNPMEAFNFVTANEDHNAYYYDMRNLSRSLNVFKDHVSAV
MDVDFSPTGDEIVTGSYDKSIRIYKTNHGHSREIYHTKRMQHVFQVKYSM
DSKYIISGSDDGNVRLWRSKAWERSNVKTTREKNKLEYDEKLKERFRHMP
EIKRISRHRHVPQVIKKAQEIKNIELSSIKRREANERRTRKDMPYISERK
KQIVGTV
Ligand information
>5wlc Chain L2 (length=169) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucgacguacuucauaggaucauuucuauaggaaucgucacucuuugacu
cuucaaaagagccacugaauccaacuugguugaugagucccauaaccuuu
guacccagugagaaaccguauggcgcgaugaucuacccauggguggguac
aaauggcagucugacaagu
..................................................
.......................<<<<<.................<<<<<
<<<<<.<<.......<<<..>>>.........>><<<<..>>>>.>>>>>
>>>.>>........>>>>>
Receptor-Ligand Complex Structure
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PDB5wlc The complete structure of the small-subunit processome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)
S18 T19 K49 R52 F54 A55 K56 P57 F58 Q61 K346 R347 R373 R382 R389 E390 L394 H418
Binding residue
(residue number reindexed from 1)
S18 T19 K49 R52 F54 A55 K56 P57 F58 Q61 K338 R339 R365 R374 R381 E382 L386 H410
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5wlc, PDBe:5wlc, PDBj:5wlc
PDBsum5wlc
PubMed28945246
UniProtP33750|DCA13_YEAST Protein SOF1 (Gene Name=SOF1)

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