Structure of PDB 6b4v Chain LB Binding Site BS03

Receptor Information
>6b4v Chain LB (length=181) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PLDLALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDAR
ILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWI
FLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDA
LRGMDIAVVTTAETDEEARALLELLGFPFRK
Ligand information
>6b4v Chain MC (length=77) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgggguggagcagccugguagcucgucgggcucauaacccgaaggucg
ucgguucaaauccggcccccgcaacca
..<<<<...<<<<.........>>>>.<<<<<.......>>>>>......
<<<<.......>>>>..>>>>......
Receptor-Ligand Complex Structure
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PDB6b4v Mechanism of Inhibition of Translation Termination by Blasticidin S.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		S76 I77 S78 R83
Binding residue
(residue number reindexed from 1)		S75 I76 S77 R82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6b4v, PDBe:6b4v, PDBj:6b4v
PDBsum6b4v
PubMed29366636
UniProtQ72I16|RL5_THET2 Large ribosomal subunit protein uL5 (Gene Name=rplE)

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