Structure of PDB 8ro2 Chain L2 Binding Site BS03

Receptor Information
>8ro2 Chain L2 (length=369) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEDTWMLPDVNERIEQFSQEHSSGVENEDQQEVILVRTDQSGRVWPVNTK
RQMVSTHEERERVRYFHDDDNLSLNDLVKNEKMGTAENQNKLFMRMASKF
MGKTDGDYYTLDDMFVSKAAERERLGEEEENQRKKAIAEHRSLAAQMEKC
LYCFDSSQFPKHLIVAIGVKVYLCLPNVRSLTEGHCLIVPLQHHRAATLL
DEDIWEEIQMFRKSLVKMFEDKGLDCIFLETNMSMKKQYHMVYECIPLPK
EVGDMAPIYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFSVDF
GLHGGFAHVIEDQHKFPHYFGKEIIGGMLDIEPRLWRKGIRESFEDQRKK
ALQFAQWWKPYDFTKSKNY
Ligand information
>8ro2 Chain IN (length=41) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
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Receptor-Ligand Complex Structure
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PDB8ro2 Mechanism for the initiation of spliceosome disassembly.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
R647 R658 K659 H839 R866
Binding residue
(residue number reindexed from 1)
R122 R133 K134 H314 R341
External links
PDB RCSB:8ro2, PDBe:8ro2, PDBj:8ro2
PDBsum8ro2
PubMed38925148
UniProtQ2TBE0|C19L2_HUMAN CWF19-like protein 2 (Gene Name=CWF19L2)

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