Structure of PDB 8uk9 Chain L Binding Site BS03

Receptor Information
>8uk9 Chain L (length=320) Species: 10665 (Tequatrovirus T4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMITVNEKEHILEQKYRPSTIDECILPAFDKETFKSITSKGKIPHIILHS
PSPGTGKTTVAKALCHDVNADMMFVNGSDCKIDFVRGPLTNFASAASFDG
RQKVIVIDEFCRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQ
SRCRVITFGQPTDEDKIEMMKQMIRRLTEICKHEGIAIADMKVVAALVKK
NFPDFRKTIGELDSYSSKGVLDAGILSLVTNDRGAIDDVLESLKNKDVKQ
LRALAPKYAADYSWFVGKLAEEIYSRVTPQSIIRMYEIVGENNQYHGIAA
NTELHLAYLFIQLACEMQWK
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain8uk9 Chain L Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8uk9 Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K56 E108 N139 R205
Binding residue
(residue number reindexed from 1)		K57 E109 N140 R206
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication
Cellular Component
GO:0005663 DNA replication factor C complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8uk9, PDBe:8uk9, PDBj:8uk9
PDBsum8uk9
PubMed38177685
UniProtP04526|LOADL_BPT4 Sliding-clamp-loader large subunit (Gene Name=44)

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