Structure of PDB 1fak Chain L Binding Site BS03

Receptor Information
>1fak Chain L (length=108) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHK
DDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPC
GKIPILEK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1fak Chain L Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1fak Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D46 G47 D48 Q49 D63 Q64
Binding residue
(residue number reindexed from 1)		D11 G12 D13 Q14 D28 Q29
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.21: coagulation factor VIIa.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1fak, PDBe:1fak, PDBj:1fak
PDBsum1fak
PubMed9925787
UniProtP08709|FA7_HUMAN Coagulation factor VII (Gene Name=F7)

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