Structure of PDB 6s91 Chain K Binding Site BS03

Receptor Information

>6s91 Chain K (length=1023) Species: 930945 (Sulfolobus islandicus REY15A)

EFLDYKIIALLHDPPNKAWVITGRARNLTQQLSRKHEKVAKYIINQLFGK
NYSEKVDNADKLASSIDRYLGSIVYKERSLFENRSIFLKNILLSNIQRDI
GNLFPKDKSKLDNLILEYKKLLNVINKTNLILKYQLFYLIYELVWIDSKY
ENTPSDTRNPTHTIFDHLYATAAMMNWILSLEKEAKGYLLGIDTIGVADF
ISKGRKTRDLWISSYLVSALLWYVITWFIEEYGPDVILFPSLRFNQFYAF
YLLEKLRKEGVSEDVIDEIKELITKYIFNGDDLFENLKIPPYPIIPGRIT
LILPGLIREGEEYKKVQDDNCFISKVKERYNEGWRKLIEGLRCYSERKRE
DGFWNLVCRVLKLTEDLLQTTPLNIRVKQVSVTEDEIFNNNKLRSDSWKI
YDNKYRQLVSEFKKSKLVKVTPESRLKLFELTKFDKLPQIGEKSKRGYEF
CTSCGVLPAVVIMPKEDELEKKLIDLGIARDEKDVRSIKNMISPGERLCP
WCLVKRALGAEPRLMRILLLGDLYSVEKIVNEIVSRDVKIEIPSTSDIAS
IKTFEEMIEKKNEICEDLKEEEVCEKPSESVLSMWQWFNKNYYNGINLTI
DPEEYWFSEKRRRYYFSVFRRHRITFPSPYYALVRADSDYLGDLLEGKLT
PYLAGIIDSGDYANISEKKEEVNKLLEEYLVNAGSGSIVDYVKTVLKCIR
ENLNKCSCAEKIYSNEVAKVMFRVNVEKANVEEEVKNSLEYFETILNEGR
IIVTPAWHVSISSALNRGLLVELELVNKHKGFVIYAGGDDLLAMLPVDEV
LDFIKESRRAFAGFGTEKLGNMCLENGFVRINNAYYPSLPIVGRSYSVII
AHYADPLFFVINDSYNLLEEGKEIIRYRVMYNGEYKDAKKDVAIFRYQGL
TSVIPLSLKRPIVSSVSDFNEIASIIDVILELKKRIDEGRISVSLLYDYE
KYKHLIVASDEKYLTEFLVKDWIKRNSLRKHVEFTIDEKLYGVRLTIENY
PIKIPNDLISNIVYTLRIIYGGE

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 6s91 Chain K Residue 1101

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6s91 Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
• Resolution: 2.68 Å
• Binding residue (original residue number in PDB): C464 C467 C512 C515
• Binding residue (residue number reindexed from 1): C451 C454 C499 C502
• Annotation score: 4

Gene Ontology

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:6s91, PDBe:6s91, PDBj:6s91
• PDBsum: 6s91
• PubMed: 32730741
• UniProt: F0NDX2