Structure of PDB 3vd0 Chain K Binding Site BS03
Receptor Information
>3vd0 Chain K (length=206) Species:
9606
(Homo sapiens) [
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HHHHHHEFIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIA
KTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEG
QSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNF
MCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADE
DHYREQ
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
3vd0 Chain K Residue 401 [
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Receptor-Ligand Complex Structure
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PDB
3vd0
Structure of p73 DNA-binding domain tetramer modulates p73 transactivation.
Resolution
2.95 Å
Binding residue
(original residue number in PDB)
C194 H197 C258 C262
Binding residue
(residue number reindexed from 1)
C88 H91 C152 C156
Annotation score
4
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000976
transcription cis-regulatory region binding
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
GO:0006915
apoptotic process
Cellular Component
GO:0005634
nucleus
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:3vd0
,
PDBe:3vd0
,
PDBj:3vd0
PDBsum
3vd0
PubMed
22474346
UniProt
O15350
|P73_HUMAN Tumor protein p73 (Gene Name=TP73)
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