Structure of PDB 8adl Chain J Binding Site BS03

Receptor Information
>8adl Chain J (length=801) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLIKKVTHWSYDNLIDYLSVNPTRDEVTHYKVDPENESDESIIKLHTVKD
FGSITCLDYSESEIGMIGVGEKNGYLRIFNISYDIRVRAKKQRCINSLGI
NTNGLIAMGLDRNKHDSSLQIWDMNYHDDSHETINPMFSYCTNESIVSLK
FLNDTSVLAASTKFLKEIDVRSPNPIYQHPTRLTYDIKLNPFNDWQFSTY
GDDGTLAIWDRRKLSDASPLLTFEKLVGSGAASRKYMNSCFRWSCVRNNE
FATLHRGDTIKRWRLGYYCDSNIENLFVSSVHDTNTMYDRVATFDYIPRS
NNGTSLICMRQSGTIYRMPISEVCSKAILNNRNSLLLSNFENTEIDEIRV
NFWKPEKLLEKDISVIMRTRASLGYGLDPMNTVEMIDSSNAYIRNTWRWI
AIAKASVDDGTMVSGDLDLGYEGVIGIWNGILSDKQLNKEMEKIIKLRAG
SPKYVQRRLCLIISGWDLSRSDYEDKYNIIMKNGHYEKAAAWAVFFGDIP
KAVEILGSAKKERLRLIATAIAGYLAYKDLPGNNAWRQQCRKMSSELDDP
YLRVIFAFIADNDWWDILYEPAISLRERLGVALRFLNDTDLTTFLDRTSS
TVIENGELEGLILTGITPNGIDLLQSYVNKTSDVQSAALISIFGSPRYFR
DQRVDEWIQTYRDMLKSWELFSMRARFDVLRSKLSRTKTGVLTADIKPRQ
IYIQCQNCKQNINTPRHKYCCPHCGSSFPRCAICLMPLGTSNLPFVINGT
NRELVSRKLKLNEWFSFCLSCNHGMHAGHAEEWFDRHNVCPTPGCTCQCN
K
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8adl Chain J Residue 1103 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8adl Cryo-EM structure of the SEA complex.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		C953 C956 H1013 H1016
Binding residue
(residue number reindexed from 1)		C731 C734 H776 H779
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0015031 protein transport
GO:1903432 regulation of TORC1 signaling
GO:1904263 positive regulation of TORC1 signaling
Cellular Component
GO:0005737 cytoplasm
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0016020 membrane
GO:0035859 Seh1-associated complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8adl, PDBe:8adl, PDBj:8adl
PDBsum8adl
PubMed36289347
UniProtP38164|SEA4_YEAST SEH-associated protein 4 (Gene Name=SEA4)

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