Structure of PDB 5ak9 Chain J Binding Site BS03
Receptor Information
>5ak9 Chain J (length=182) [
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ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITAKSENLIKQHIAP
LMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMR
EQIAFIKGLYVAEGDMTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLD
DHRHGVYVLNISLRDRIKFVHTILSSHLNPLP
Ligand information
>5ak9 Chain N (length=25) [
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cgcgccggaacttacccggcaaggc
Receptor-Ligand Complex Structure
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PDB
5ak9
Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
Resolution
2.601 Å
Binding residue
(original residue number in PDB)
N32 R33 S34 E35 Y36 R37 S67 K68 D75 R81 S83 S84 K85 E117 D119 M120 R126 W128 N129 K130 D155 H158
Binding residue
(residue number reindexed from 1)
N28 R29 S30 E31 Y32 R33 S63 K64 D71 R77 S79 S80 K81 E113 D115 M116 R122 W124 N125 K126 D151 H154
Binding affinity
PDBbind-CN
: Kd=0.3nM
Enzymatic activity
Enzyme Commision number
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519
endonuclease activity
Biological Process
GO:0006314
intron homing
GO:0016539
intein-mediated protein splicing
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Molecular Function
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Biological Process
External links
PDB
RCSB:5ak9
,
PDBe:5ak9
,
PDBj:5ak9
PDBsum
5ak9
PubMed
26045557
UniProt
P21505
|DMO1_DESMO Homing endonuclease I-DmoI
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