Structure of PDB 8g2j Chain I Binding Site BS03

Receptor Information
>8g2j Chain I (length=720) Species: 143775 (Populus tremula x P. tremuloides/Amanita muscaria mixed EST library) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPLSIVYPIPRNKLTPYRAVIIMRLIILGLFFHYRITNPVDSAFGLWLTS
VICEIWFAFSWVLDQFPKWKPVNRETFIERLSARYEREGEPSQLAAVDFF
VSTVDPLKEPPLITANTVLSILAVDYPVDKVSCYVSDDGAAMLTFESLVE
TAEFARKWVPFCKKFSIEPRAPEFYFSQKIDYLKDKVQPSFVKERRAMKR
DYEEYKVRVNALVAKAQKTPDEGWTMQDGTPWPGNNTRDHPGMIQVFLGN
TGARDIEGNELPRLVYVSREKRPGYQHHKKAGAENALVRVSAVLTNAPYI
LNLDCDHYVNNSKAVREAMCILMDPQVGRDVCYVQFPQRFDGIDRSDRYA
NRNIVFFDVNMKGLDGIQGPMYVGTGCVFNRQALYGYGPPSMPRLSQLSF
EKTFGLSPVFIESTLMENGGVPESANSSTLIKEAIHVIGCGFEEKTEWGK
EIGWIYGSVTEDILSGFKMHCRGWRSIYCMPVRPAFKGSAPINLSDRLHQ
VLRWALGSVEIFFSRHCPFWYGYGGGRLKWLQRLAYINTIVYPFTSLPLI
AYCTIPAVCLLTGKFIIPTLSNLASMLFLGLFISIIVTAVLELRWSGVSI
EDLWRNEQFWVIGGVSAHLFAVFQGFLKMLAGVKWTTLLIPPTTLLIINI
VGVVAGFSDALNKGYEAWGPLFGKVFFAFWVILHLYPFLKGLMGRQNRTP
TIVVLWSVLLTSVFSLVWVK
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain8g2j Chain B Residue 5 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8g2j Insights into substrate coordination and glycosyl transfer of poplar cellulose synthase-8.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		N509 I677 W718
Binding residue
(residue number reindexed from 1)		N353 I463 W504
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.12: cellulose synthase (UDP-forming).
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0016759 cellulose synthase activity
GO:0016760 cellulose synthase (UDP-forming) activity
GO:0046872 metal ion binding
Biological Process
GO:0009833 plant-type primary cell wall biogenesis
GO:0030244 cellulose biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8g2j, PDBe:8g2j, PDBj:8g2j
PDBsum8g2j
PubMed36798277
UniProtQ6J8X0

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