Structure of PDB 7arc Chain I Binding Site BS03

Receptor Information
>7arc Chain I (length=199) Species: 37502 (Polytomella sp. Pringsheim 198.80) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTERRPGQSGAWKQVDKQRYSSEWEQDPTFKQVPKNVSEVLDDSVSVLFL
TDIVRGMMYSASGFFDDKVTILYPFEKGAVSPRFRGEHALRRYPTGEERC
ISCKLCEAICPAQAITIEAEEREDGSRKTTRYDIDMTKCIYCGFCQEACP
VDAIVEGPNFEFSTETREELLYDKQKLLENGDKWEQEIAANLRTESLYR
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7arc Chain I Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7arc A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Resolution2.88 Å
Binding residue
(original residue number in PDB)		C130 I131 S132 C133 K134 C136 Y162 C179 A183 I184
Binding residue
(residue number reindexed from 1)		C100 I101 S102 C103 K104 C106 Y132 C149 A153 I154
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7arc, PDBe:7arc, PDBj:7arc
PDBsum7arc
PubMed33768254
UniProtA0A7S0UQ60

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