Structure of PDB 5zlp Chain I Binding Site BS03

Receptor Information
>5zlp Chain I (length=475) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSESKIKEFFEFCKENEVEFVDFRFSDIKGTWNHIAYSFGALTHGMLKEG
IPFDASCFKGWQGIEHSDMILTPDLVRYFIDPFSADVSVVVFCDVYDVYK
NQPYEKCPRSIAKKALQHLKDSGLGDVAYFGAENEFFIFDSIKIKDASNS
QYYEVDSEEGEWNRDRSFENGVNFGHRPGKQGGYMPVPPTDTMMDIRTEI
VKVLNQVGLETFVVHHEVAQAQGEVGVKFGDLVEAADNVQKLKYVVKMVA
HLNGKTATFMPKPLYGDNGSGMHTHVSVWKNNENLFSGETYKGLSEFALH
FLGGVLRHARGLAAFTNASTNSYKRLIPGYEAPSILTYSANNRSASVRIP
YGISKNSARFEFRFPDSSSNPYLAFAAILMAGMDGVKNKIDPGEAMDINL
FKLTLDEIREKGIKQMPHTLRRSLEEMLADKQYLKESQVFSEEFIQAYQS
LKFNAEVFPWESKPHPFEFITTYSC
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5zlp Chain I Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5zlp Structural Analysis of Glutamine Synthetase from Helicobacter pylori.
Resolution2.93 Å
Binding residue
(original residue number in PDB)		E141 E223 E230
Binding residue
(residue number reindexed from 1)		E135 E217 E224
Annotation score1
Enzymatic activity
Enzyme Commision number 6.3.1.2: glutamine synthetase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004356 glutamine synthetase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006542 glutamine biosynthetic process
GO:0019740 nitrogen utilization
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5zlp, PDBe:5zlp, PDBj:5zlp
PDBsum5zlp
PubMed30076387
UniProtP94845|GLN1B_HELPY Glutamine synthetase (Gene Name=glnA)

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