Structure of PDB 4esv Chain I Binding Site BS03

Receptor Information
>4esv Chain I (length=418) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IPPQSIEAEQAVLGAVFLDPAALVPASEILIPEDFYRAAHQKIFHAMLRV
ADRGEPVDLVTVTAELAASEQLEEIGGVSYLSELADAVPTAANVEYYARI
VEEKSVLRRLIRTATSIAQDGYTREDEIDVLLDEADRKIMEFKNIKDILV
QTYDNIEMLITGIPTGFTELDRMTSGFQRSDLIIVAARPSVGKTAFALNI
AQNVATKTNENVAIFSLEMSAQQLVMRMLCAEGNINAQNLRTGKLTPEDW
GKLTMAMGSLSNAGIYIDDTPSIRVSDIRAKCRRLKQESGLGMIVIDYLQ
LIQGSGRSKENRQQEVSEISRSLKALARELEVPVIALSQLSRSVEQRQDK
RPMMSDIRESGSIEQDADIVAFLYRDDYYNKDSENKNIIEIIIAKQRNGP
VGTVQLAFIKEYNKFVNL
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain4esv Chain I Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4esv The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		K216 E241 Q362
Binding residue
(residue number reindexed from 1)		K193 E218 Q339
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
Cellular Component
GO:0005829 cytosol
GO:1990077 primosome complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4esv, PDBe:4esv, PDBj:4esv
PDBsum4esv
PubMed23022319
UniProtQ9X4C9|DNAB_GEOSE Replicative DNA helicase DnaB (Gene Name=dnaB)

[Back to BioLiP]