Structure of PDB 8jp5 Chain H Binding Site BS03

Receptor Information
>8jp5 Chain H (length=98) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LDKNTVHDQEHIMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDG
LELSTAITHVHQAPLMSEDELINIIDGVLRDDDKNNDGYIDYAEFAKS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8jp5 Chain H Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8jp5 Structure of full-length ERGIC-53 in complex with MCFD2 for cargo transport.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		H51 H55 H99 H101
Binding residue
(residue number reindexed from 1)		H11 H15 H59 H61
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0012507 ER to Golgi transport vesicle membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8jp5, PDBe:8jp5, PDBj:8jp5
PDBsum8jp5
PubMed38493152
UniProtQ8NI22|MCFD2_HUMAN Multiple coagulation factor deficiency protein 2 (Gene Name=MCFD2)

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