Structure of PDB 8gan Chain H Binding Site BS03

Receptor Information

>8gan Chain H (length=582) Species: 486 (Neisseria lactamica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MILHALTQYYQRKAESDGGIAQEGFENKEIPFIIVIDKQGNFIQLEDTRE
LKVKKKVGRTFLVPKGLGRSGSKSYEVSNLLWDHYGYVLAYAGEKGQEQA
DKQHASFTAKVNELKQALPDDAGVTAVAAFLSSAEEKSKVMQAANWAECA
KVKGCNLSFRLVDEAVDLVCQSKAVREYVSQANQTQSDNAQKGICLVTGK
AAPIARLHNAVKGVNAKPAPFASVNLSAFESYGKEQGFAFPIGEQAMFEY
TTALNTLLAGENRFRIGDVTTVCWGAKRTPLEESLASMINGGGKDNPDAH
IDAVKALYKSLYNGQYCKPDGEDKFYLLGLSPNSARIVVRFWHETTVAAL
SESIAAWYDDLQMVRGENSPYPEYMPLPRLLGNLVLDGKMENLPSDLIAQ
ITDAALNNRVLPVSLLQAALRRNKAEQKITYGRASLLKAYINRAIRAGRL
KNMKELTMGLDRNRQDIGYVLGRLFAVLEKIQAEANPGLNATIADRYFGS
ASSTPIAVFGTLMRLLPHHLNKLEFEGRAVQLQWEIRQILEHCQRFPNHL
NLEQQGLFAIGYYHETQFLFTKDALKNLFNEA

Ligand information

>8gan Chain O (length=19) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

atgaacttcaaaaaaaaaa

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8gan Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Resolution	3.26 Å
Binding residue (original residue number in PDB)	K52 K54 R69 S70 G71 K95 Q99 K153 G154 N215 A216 K217 P218 R263 R265 K309 Y312 N313 Q315 P372 P378 R379
Binding residue (residue number reindexed from 1)	K52 K54 R69 S70 G71 K95 Q99 K153 G154 N215 A216 K217 P218 R263 R265 K309 Y312 N313 Q315 P372 P378 R379

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:8gan, PDBe:8gan, PDBj:8gan
PDBsum	8gan
PubMed	38242128
UniProt	D0W8X5

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