Structure of PDB 3vxf Chain H Binding Site BS03
Receptor Information
>3vxf Chain H (length=257) Species:
9606
(Homo sapiens) [
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IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPW
DKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDI
ALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTA
NVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDA
CEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI
QKVIDQF
Ligand information
>3vxf Chain I (length=3) Species:
32644
(unidentified) [
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FPR
Receptor-Ligand Complex Structure
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PDB
3vxf
Neutron and X-ray crystallographic analysis of the human alpha-thrombin-bivalirudin complex at pD 5.0: protonation states and hydration structure of the enzyme-product complex
Resolution
1.602 Å
Binding residue
(original residue number in PDB)
H57 Y60A D189 A190 G193 S195 S214 W215 G216 G219
Binding residue
(residue number reindexed from 1)
H43 Y47 D199 A200 G203 S205 S226 W227 G228 G230
Enzymatic activity
Enzyme Commision number
3.4.21.5
: thrombin.
External links
PDB
RCSB:3vxf
,
PDBe:3vxf
,
PDBj:3vxf
PDBsum
3vxf
PubMed
23712263
UniProt
P00734
|THRB_HUMAN Prothrombin (Gene Name=F2)
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