Structure of PDB 8q3m Chain GGG Binding Site BS03

Receptor Information
>8q3m Chain GGG (length=107) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEI
LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQ
AVLLPKK
Ligand information
>8q3m Chain MMM (length=14) Species: 37296 (Human gammaherpesvirus 8) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PGPRLRSGRSTGAP
Receptor-Ligand Complex Structure
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PDB8q3m Viral peptide conjugates for metal-warhead delivery to chromatin.
Resolution2.503 Å
Binding residue
(original residue number in PDB)
Y57 E61 E64 D90 E92
Binding residue
(residue number reindexed from 1)
Y45 E49 E52 D78 E80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8q3m, PDBe:8q3m, PDBj:8q3m
PDBsum8q3m
PubMed38495982
UniProtP04908|H2A1B_HUMAN Histone H2A type 1-B/E (Gene Name=H2AC4)

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