Structure of PDB 8i02 Chain G Binding Site BS03

Receptor Information
>8i02 Chain G (length=284) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NNDYCSACHGPGNFLCCETCPNSFHFTCIDPPIEEKNLPDDAWYCNTMVD
VWMQLCTYIDSHNPIQFHLPHSISSFFRGVGSGVMGEYIETDVLKRDPLL
LKSKSGTPILCFRCHKSALVSQSILACDYCNSYWHPDCLNPPLATLPSNL
RKWKCPNHSDHVTPRYRLPEKAKVIRVGLPRGFKNKGNIVIDFKLNFLEQ
IRDNVINLRKMVEQDEQLCIETFSKFDFYATRDCELPLRILCDVANDNLE
NDDYVLALRDLLRISKWDPNQPVPAPFDLANLLS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8i02 Chain G Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8i02 Two assembly modes for SIN3 histone deacetylase complexes.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		C425 C428 C453
Binding residue
(residue number reindexed from 1)		C127 C130 C155
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0060090 molecular adaptor activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0045815 transcription initiation-coupled chromatin remodeling
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0032221 Rpd3S complex
GO:0032991 protein-containing complex
GO:0072686 mitotic spindle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i02, PDBe:8i02, PDBj:8i02
PDBsum8i02
PubMed37076472
UniProtQ09698|YA27_SCHPO Uncharacterized protein C2F7.07c (Gene Name=SPAC2F7.07c)

[Back to BioLiP]