Structure of PDB 3ny2 Chain G Binding Site BS03

Receptor Information
>3ny2 Chain G (length=73) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGSLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSG
GGGFCDCGDTEAWKEGPYCQKHE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3ny2 Chain G Residue 21 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ny2 Structural basis of substrate recognition and specificity in the N-end rule pathway.
Resolution2.61 Å
Binding residue
(original residue number in PDB)		C112 C115 H133 H136
Binding residue
(residue number reindexed from 1)		C18 C21 H39 H42
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:3ny2, PDBe:3ny2, PDBj:3ny2
PDBsum3ny2
PubMed20835242
UniProtQ8IWV8|UBR2_HUMAN E3 ubiquitin-protein ligase UBR2 (Gene Name=UBR2)

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