Structure of PDB 1id3 Chain G Binding Site BS03

Receptor Information

>1id3 Chain G (length=108) Species: 4932 (Saccharomyces cerevisiae)

KASQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAE
ILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNI
HQNLLPKK

Ligand information

• Ligand ID: MN
• InChI: InChI=1S/Mn/q+2
• InChIKey: WAEMQWOKJMHJLA-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mn+2]
  CACTVS 3.341: [Mn++]
• Formula: Mn
• Name: MANGANESE (II) ION
• DrugBank: DB06757
• PDB chain: 1id3 Chain G Residue 132

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1id3 Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): D91 E93
• Binding residue (residue number reindexed from 1): D79 E81
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0005515 protein binding
• GO:0030527 structural constituent of chromatin
• GO:0031492 nucleosomal DNA binding
• GO:0046982 protein heterodimerization activity

Biological Process

• GO:0000122 negative regulation of transcription by RNA polymerase II
• GO:0006281 DNA repair
• GO:0006325 chromatin organization
• GO:0031507 heterochromatin formation

Cellular Component

• GO:0000786 nucleosome
• GO:0005634 nucleus
• GO:0005694 chromosome
• GO:0031298 replication fork protection complex
• GO:0032991 protein-containing complex

External links

• PDB: RCSB:1id3, PDBe:1id3, PDBj:1id3
• PDBsum: 1id3
• PubMed: 11566884
• UniProt: P04911|H2A1_YEAST Histone H2A.1 (Gene Name=HTA1)