Structure of PDB 1g21 Chain G Binding Site BS03

Receptor Information

>1g21 Chain G (length=268) Species: 354 (Azotobacter vinelandii)

MRQCAIYGKGGIGKSTTTQNLVAALAEMGKKVMIVGCDPKADSTRLILHS
KAQNTIMEMAAEAGTVEDLELEDVLKAGYGGVKCVESGGPEPGVGCAGRG
VITAINFLEEEGAYEDDLDFVFYDVGDVVCGGFAMPIRENKAQEIYIVCS
GEMMAMYAANNISKGIVKYANSGSVRLGGLICNSRNTDREDELIIALANK
LGTQMIHFVPRDNVVQRAEIRRMTVIEYDPKAKQADEYRALARKVVDNKL
LVIPNPITMDELEELLME

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 1g21 Chain H Residue 293

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1g21 MgATP-Bound and nucleotide-free structures of a nitrogenase protein complex between the Leu 127 Delta-Fe-protein and the MoFe-protein.
• Resolution: 3.0 Å
• Binding residue (original residue number in PDB): S16 D125
• Binding residue (residue number reindexed from 1): S15 D124
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): K10 G12 K15 K41 D129
• Catalytic site (residue number reindexed from 1): K9 G11 K14 K40 D127
• Enzyme Commision number: 1.18.6.1: nitrogenase.

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016163 nitrogenase activity
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0009399 nitrogen fixation

External links

• PDB: RCSB:1g21, PDBe:1g21, PDBj:1g21
• PDBsum: 1g21
• PubMed: 11170380
• UniProt: P00459|NIFH1_AZOVI Nitrogenase iron protein 1 (Gene Name=nifH1)