Structure of PDB 7rdq Chain F Binding Site BS03

Receptor Information
>7rdq Chain F (length=349) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ISTSDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDP
DLIREVVRAKILGSARVRHIPGLKETLDPKTVEEIDQKLKSLPKEHKRYL
HIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAV
EKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRT
ARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDE
KDSFYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKG
LIDGREHTLEEVGAFFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD
Ligand information
Receptor-Ligand Complex Structure
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PDB7rdq Structural and mechanistic basis of reiterative transcription initiation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		I75 S76 T77 D323 E324 K325 D326
Binding residue
(residue number reindexed from 1)		I1 S2 T3 D249 E250 K251 D252
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7rdq, PDBe:7rdq, PDBj:7rdq
PDBsum7rdq
PubMed35082149
UniProtQ5SKW1

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