Structure of PDB 6t66 Chain F Binding Site BS03

Receptor Information
>6t66 Chain F (length=442) Species: 666 (Vibrio cholerae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKVPPHSLEAEQSVIGGLLLDNERWDTVSEHVMTQDFYSRPHRLIFDGVK
SILEAGKPLDLITLSEYLEQREQLEDVGGFAYLADLAKNTPSAANINAYA
EIVAERALVRNLIGVANEIADAGYDPQGRNAEDLLDLAESKVFAIAEART
SENEGPKNVDSILERTLERIELLYKTPQDGVTGVNTGFTDLNKKTAGLQG
SDLIIVAARPSMGKTTFAMNLCENAAMEQDKPVLIFSLEMPAEQIMMRML
ASLSRVDQTKIRTGQLDDEDWARISSTMGILMEKKNMYIDDSSGLTPTEV
RSRARRIAREHGGLSLIMVDYLQLMRVPALTDNRTLEIAEISRSLKALAK
ELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEV
YHPDSPLKGTAEIIIGKQRNGPIGSVRLTFQGHYSRFDNYAG
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain6t66 Chain F Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6t66 Study of the DnaB:DciA interplay reveals insights into the primary mode of loading of the bacterial replicative helicase.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		K234 E259 Y341
Binding residue
(residue number reindexed from 1)		K214 E239 Y321
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006269 DNA replication, synthesis of primer
Cellular Component
GO:0005829 cytosol
GO:1990077 primosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6t66, PDBe:6t66, PDBj:6t66
PDBsum6t66
PubMed34107018
UniProtQ9KUY7

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