Structure of PDB 6bk8 Chain F Binding Site BS03

Receptor Information

>6bk8 Chain F (length=199) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DEINEPPPNICEQCLGDEANIRMTKIPQGSECKICTLPFTLYHFKTSKRS
NNIIKTLICVRCATQRNICQCCMLDSRWHIPIQLRDHLISLVNEENVMTE
EAKNDMMKRFLSLKNVKLGGAQITSDPSEADNIVDKLKNILLRATKSFFL
YNIDASIPEWKITDTVSQLLLSLIVNHKAKCGGLRFQSSELGERFVSKI

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

6bk8 Chain F Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6bk8 Structure of the yeast spliceosomal postcatalytic P complex.
Resolution	3.3 Å
Binding residue (original residue number in PDB)	C34 C37 C61 C64
Binding residue (residue number reindexed from 1)	C32 C35 C59 C62
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0017070	U6 snRNA binding
GO:0036002	pre-mRNA binding

	Biological Process
GO:0000398	mRNA splicing, via spliceosome
GO:0006397	mRNA processing
GO:0008380	RNA splicing

	Cellular Component
GO:0000974	Prp19 complex
GO:0005634	nucleus
GO:0005681	spliceosomal complex
GO:0071006	U2-type catalytic step 1 spliceosome
GO:0071007	U2-type catalytic step 2 spliceosome

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Biological Process

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Cellular Component

External links

PDB	RCSB:6bk8, PDBe:6bk8, PDBj:6bk8
PDBsum	6bk8
PubMed	29146870
UniProt	P38241\|SLT11_YEAST Pre-mRNA-splicing factor SLT11 (Gene Name=ECM2)

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