Structure of PDB 5cb6 Chain F Binding Site BS03

Receptor Information

>5cb6 Chain F (length=173) Species: 1111708 (Synechocystis sp. PCC 6803 substr. Kazusa)

RGVTIWLTGLSGAGKTTITHALEKKLRDSGYRLEVLDGDVVRTNLTKGLG
FSKEDRDTNIRRIGFVSHLLTRNGVIVLVSAISPYAAIRQEVKHTIGDFL
EVFVNAPLAVCEERDVKGLYAKARSGEIKGFTGIDDPYEPPTNPDVECRT
DLEELDESVGKIWQKLVDLKYIE

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 5cb6 Chain F Residue 303

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5cb6 Recapitulating the Structural Evolution of Redox Regulation in Adenosine 5'-Phosphosulfate Kinase from Cyanobacteria to Plants.
• Resolution: 2.79 Å
• Binding residue (original residue number in PDB): T19 D40 D42
• Binding residue (residue number reindexed from 1): T16 D37 D39
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.7.1.25: adenylyl-sulfate kinase.

Gene Ontology

Molecular Function

• GO:0004020 adenylylsulfate kinase activity
• GO:0004781 sulfate adenylyltransferase (ATP) activity
• GO:0005524 ATP binding
• GO:0016301 kinase activity

Biological Process

• GO:0000103 sulfate assimilation
• GO:0010134 sulfate assimilation via adenylyl sulfate reduction
• GO:0016310 phosphorylation
• GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)
• GO:0070814 hydrogen sulfide biosynthetic process

External links

• PDB: RCSB:5cb6, PDBe:5cb6, PDBj:5cb6
• PDBsum: 5cb6
• PubMed: 26294763
• UniProt: P72940|CYSC_SYNY3 Probable adenylyl-sulfate kinase (Gene Name=cysC)